Table 3 Odds ratios (ORs) and confidence intervals (CIs) of ovarian cancer in association with prevalent co-morbidities by histology groups

From: Evaluation of prevalent and incident ovarian cancer co-morbidity

 

High-risk epithelial tumours a

Medium-risk epithelial tumours b

 

Cases ( n =8567)/controls ( n =42 835)

OR

95% CI

Cases (1504)/controls ( n =7518)

OR

95% CI

Haematologic complications

388/592

3.4

(3.0–3.9)

66/86

3.9

(2.8–5.4)

Thyroid disease

201/485

2.1

(1.8–2.5)

28/78

1.8

(1.2–2.8)

Cardiovascular disease

818/3498

1.2

(1.1–1.3)

106/494

1.1

(0.9–1.4)

Cerebrovascular event

268/1433

0.9

(0.8–1.1)

44/180

1.2

(0.9–1.7)

Thromboembolic events

267/566

2.4

(2.1–2.8)

58/105

2.9

(2.1–4.0)

Hypertension

862/2206

2.1

(2–2.3)

133/307

2.4

(1.9–2.9)

Pulmonary disease

123/584

1.1

(0.9–1.3)

15/72

1.0

(0.6–1.8)

GI complications

743/1937

2.0

(1.9–2.2)

116/281

2.2

(1.7–2.8)

Diabetes mellitus

343/1143

1.5

(1.4–1.7)

58/143

2.1

(1.5–2.9)

Liver/pancreatic disease

110/363

1.5

(1.2–1.9)

25/65

1.9

(1.2–3.1)

Urinary tract complications

43/124

1.7

(1.2–2.5)

7/19

1.9

(0.8–4.4)

Infectious complications

539/1513

1.8

(1.7–2.0)

83/226

1.9

(1.5–2.5)

Neoplasms

691/1988

1.8

(1.7–2.0)

128/310

2.2

(1.8–2.7)

  1. Abbreviation: GI=gastrointestinal.
  2. aHigh-risk epithelial tumours included serous and endometroid adenocarcinomas, anaplastic, small cell and poorly differentiated carcinomas.
  3. bMedium-risk epithelial tumours included mucinous adenocarcinomas, clear cell carcinomas and mesonefroid cancers.