Table 1 Comparison of clinico-pathological characteristics in young vs old women
From: Tumour biomarker expression relative to age and molecular subtypes of invasive breast cancer
Variables | ⩽40 years | ⩾50 years | P -value a |
|---|---|---|---|
Age (Mean) | 34.6 | 61.8 | <0.00 |
Race | 162 (%) | 100 (%) | <0.00 |
Caucasian | 32 (19.8) | 46 (46) | |
African American | 54 (33.3) | 36 (36) | |
Hispanic | 69 (42.6) | 16 (16) | |
Other | 7 (4.32) | 2 (2) | |
Grade | 153 | 96 | <0.00 |
1 | 9 (5.9) | 11 (11.4) | |
2 | 31 (20.2) | 47 (49.0) | |
3 | 113 (73.9) | 38 (39.6) | |
DNA ploidy | 150 | 98 | 0.11 |
Aneuploid | 112 (74.7) | 64 (65.3) | |
Diploid | 38 (25.3) | 34 (34.7) | |
Tumour size (cm) | 4.33±3.27 | 3.30±3.18 | 0.01 |
Tumour stage | 155 | 97 | 0.02 |
1 | 37 (23.9) | 38 (39.2) | |
2 | 63 (40.7) | 34 (35.0) | |
3 | 32 (20.6) | 19 (19.6) | |
4 | 23 (14.8) | 6 (6.2) | |
Nodal stage | 147 | 97 | 0.00 |
0 | 43 (29.2) | 48 (49.5) | |
1 | 77 (52.4) | 33 (34.0) | |
2 | 10 (6.8) | 9 (9.3) | |
3 | 17 (11.6) | 7 (7.2) | |
Clinical stage | 161 | 100 | 0.00 |
I | 22 (13) | 29 (29) | |
II | 61 (38) | 40 (40) | |
III | 62 (39) | 28 (28) | |
IV | 16 (10) | 3 (3) | |
Treatment | |||
Pre-surgical therapy | 151 | 100 | 0.03 |
Yes | 56 (37.1) | 24 (24) | |
No | 95 (62.9) | 76 (76) | |
Surgery | 141 | 100 | 0.00 |
Partial mastectomy | 53 (37.6) | 56 (56) | |
Radical mastectomy | 57 (40.4) | 19 (19) | |
Total mastectomy | 21 (14.9) | 24 (24) | |
Bilateral total mastectomy | 10 (7.1) | 1 (1) | |
Post-surgical therapy | 134 | 71 | |
Chemotherapy | 36 (26.9) | 31 (43.7) | 0.00 |
Radiation | 35 (26.1) | 6 (8.4) | |
Chemotherapy and radiation | 63 (47.0) | 34 (47.9) | |
Hormonal therapy | 134 | 71 | 0.00 |
Yes | 70 (52.2) | 41 (57.7) | |
No | 64 (47.8) | 30 (42.3) | |
