Table 6 Means and range of carboplatin doses (mg) as calculated by the rGFR, MDRD eGFR, CKD-EPI eGFR and CG eGFR

From: Overestimation of carboplatin doses is avoided by radionuclide GFR measurement

 

Carboplatin doses (mg)

rGFR (ml min−1 per 1.73 m2)

rGFR

MDRD

CKD-EPI

CG

Overall (n=175)

458 (230–790)

519 (280–1150)

529 (270–1020)

503 (250–1120)

<30 (n=7)

258 (230–290)

310 (280–360)

307 (270–360)

295 (250–370)

30–59 (n=84)

383 (270–500)

464 (280–700)

472 (290–700)

445 (300–790)

60–89 (n=85)

511 (350–720)

563 (380–1150)

575 (380–1020)

545 (330–1120)

⩾90 (n=13)

645 (550–790)

637 (340–860)

660 (340–830)

667 (260–960)

  1. Abbreviations: CG=Cockcroft-Gault; CKD-EPI=chronic kidney disease epidemiology collaboration; eGFR=estimated glomerular filtration rate; MDRD=modification of diet in renal disease; rGFR=radionuclide glomerular filtration rate.
  2. Data presented as mean (range).
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