Figure 4
Kaplan–Meier analysis after the completion of treatment (18 months) with ZOL in BC patients. (A) β-isomer of carboxy-terminal telopeptide of collagen I (β-CTX) and overall survival. Stratification was performed using the cutoff point obtained from the ROC curves of ‘baseline values of biomarkers at the beginning of the study’ against death. (B) Bone alkaline phosphatase (BALP) and overall survival. Stratification was performed using the cutoff point obtained from the ROC curves of ‘baseline values of biomarkers at the beginning of the study’ against death. (C) Amino-terminal propeptide of procollagen I (PINP) and new SRE. Stratification was performed using relative changes between visit 0 and visit 1 (v1/v0) in relation to cutoff point obtained from the ROC curves against death.
