Figure 4

The BMSC/IFN-β inhibits HCC cell proliferation in vivo. (A) The HE staining for xenografted tumour nodules excised from experimental mice is shown in the picture. (B) Huh7 cells were injected into the groins of athymic mice. Tumour volumes were measured on the indicated days. Representative graph of tumour growth and mean tumour 36 days after inoculation are shown. All data are shown as mean±s.d. (C) At the experimental end point, mice were anaesthetised and killed, and tumours were dissected and photographed. (D) Each tumour formed by indicated cells was weighed. (E) Immunohistochemical (IHC) staining and quantification of the expression of Ki-67 in HCC lesion. All data are shown as mean±s.d. Each bar represents the mean of three independent experiments *P<0.05.