Figure 1 | British Journal of Cancer

Figure 1

From: Changes in tumour vessel density upon treatment with anti-angiogenic agents: relationship with response and resistance to therapy

Figure 1

Correlation of imaging features with change in lesion size and patient outcome. (A) Analysis of correlation between the baseline nE and the percentage change in the lesion size (baseline to the first on-treatment scan). Baseline nE is measured in normalised mean Hounsfield Units (nHU). (r=−0.142, P=0.3). (B) An analysis of the correlation between the change in nE (baseline to the first on-treatment scan) and percentage change in lesion size (baseline to the first on-treatment scan; r=0.654, P<0.0001). Change in nE is measured in percentage. (C) Kaplan–Meier analysis: PFS of patients with baseline nE greater than the median (>0.39 nHU) and baseline nE less than the median (<0.39 nHU), P=0.2. (D). Kaplan–Meier analysis: PFS of patients with the change in nE greater than the median (>51.1%) and change nE less than the median (<51.1%), P=0.9. (E) Kaplan–Meier analysis: PFS of patients with a partial response (PR), stable disease (SD) or progressive disease (PD) according to modified Choi criteria, P=0.05.

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