Figure 3

Representative axial images from individual lesions at the baseline and at the first on-treatment scan. Pseudo-coloured arterial phase contrast-enhanced CT images of individual lesions from response subgroups 1, 2, 3 and 4 are shown. In each panel, the left hand image is the baseline scan and the right hand image is the first on-treatment scan. (A) Hilar node metastasis from a 57-year-old man treated with pazopanib (response subgroup 1). (B) Lung metastasis from a 79-year-old woman treated with pazopanib (response subgroup 1). (C) Pancreatic metastasis from an 82-year-old man treated with pazopanib (response subgroup 2). (D) Pleural metastasis from a 52-year-old woman treated with sunitinib (response subgroup 3). (E) Pre-tracheal lymph node metastasis from a 64-year-old man treated with sunitinib (response subgroup 3). (F) Liver metastasis from a 65-year-old man treated with cediranib (response group 4). (G) Waterfall plot shows the percentage change in lesion size (black) and the percentage change in nE (red) between the baseline and first on-treatment scan for each of the lesions depicted in panels (A–F).