Table 4 Published multivariate analyses of neutrophil-to-lymphocyte ratio in malignant mesothelioma
From: Existing models, but not neutrophil-to-lymphocyte ratio, are prognostic in malignant mesothelioma
Meniawy et al (this study) | |||||
|---|---|---|---|---|---|
Total no. of study patients | 173 | 85 | 171 | 148 | 274 |
No. in multivariate model | NR | NR | NR | 130 | 274 |
No. with NLR available | 168 (97%) | 84 (99%) | 159 (94%) | 79 (53%) | 274 (100%) |
Chemotherapy | Extrapleural | Chemotherapy (41%) | Chemotherapy (53%) | Chemotherapy (62%) | |
Treatments received | First line (69%) | pneumonectomy | Supportive care (42%) | Radiotherapy (34%) | Supportive care (38%) |
Second line (31%) | (EPP) | Unknown (17%) | EPP (5%) | EPP (1%) | |
Median baseline NLR | NR | 3 | NR | 3.5 | 3.5 |
Cutoff used in analysis | <5 vs ⩾5 | <3 vs ⩾3 | <5 vs ⩾5 | <3 vs ⩾3 | <5 vs ⩾5 |
Prognostic variables entered into final multivariate model | |||||
Age | NS | NS | + | ||
Gender | NS | NS | NS | NS | NS |
Nonepithelioid histology | + | NS | NS | + | + |
Sarcomatous histology | + | ||||
Stage | + | NS | |||
Performance status | NS | + | |||
Weight loss | + | ||||
Chest pain | + | ||||
Hb level | + | NS | |||
White cell count | NS | NS | NS | NS | |
Platelet count | NS | NS | + | ||
Baseline NLR | + | + | + | + | NS |
Calretinin score | + | ||||
mGPS | + | ||||
Albumin, EPS, CRP, PLR | NS | ||||
Treatments received | NS | + | |||
