Figure 3 | British Journal of Cancer

Figure 3

From: Sigma-2 receptor ligand as a novel method for delivering a SMAC mimetic drug for treating ovarian cancer

Figure 3

SW IV-52s and SW III-123 rapidly degraded cIAP1 and cIAP2 and cleaved pro-caspase-8, -9, and -3. (A) SKOV-3 cells were treated with 0, 1, 3 and 10  μ M SW 43, SW IV-52s or SW III-123 for 24 h. The whole-cell lysates were analysed by western blot. (B) SKOV-3 cells were treated with 3 μ M of SW 43, SW IV-52s or SW III-123 for indicated time. The whole-cell lysates were analysed by western blot.

Back to article page