Figure 2
The CD44+/CD24−/low cells induced (from MCF7 cells) by cytokines, except for TGF- β 1, acquired some more malignant properties but not tumour-initiating capacity. (A) The tumour volumes were measured after 1 × 106 induced cells were injected into NOD/SCID mice. (B) The induced cells spent less time to form palpable tumours than control parental cells. (C) The induced cells displayed enhanced proliferation potential compared with control parental cells. (D) The induced cells had reduced doxorubicin-induced death compared with control parental cells. (E) The induced cells had increased resistance to radiation compared with control parental cells. (F) The induced cells had increased migration compared with control parental cells.
