Figure 4
Mesenchymal–epithelial transition does not result in loss of tumour-initiating capacity in mesenchymal-like breast cancer cell lines. (A) The miR-200c-overexpressed cells had almost the same frequencies of tumour formation in NOD/SCID mice on 80 days as compared with miR-NC-overexpressed cells. (B) The miR-200c-overexpressed cells exhibited slower tumour growth in vivo than did the control cells when 5 × 106 cells were injected into the breast of 4-week-old female NOD/SCID mice.
