Table 1 Tumour-forming rates of the CD44+/CD24−/low cells induced by cytokines

From: Tumour-initiating capacity is independent of epithelial–mesenchymal transition status in breast cancer cell lines

 

80 Days a

120 Days a

 

Cells per injection

Cells per injection

Cells

1 × 10 6

1 × 10 4

1 × 10 3

1 × 10 6

1 × 10 4

1 × 10 3

MCF7

Parental cells

3/3

1/4

0/4

3/3

4/4

2/4

IL-6

3/3

2/4

0/4

3/3

4/4

1/4

EGF+bFGF

3/3

2/4

0/4

3/3

3/4

2/4

TGF-β

2/3

1/4

0/4

2/3

2/4

0/4

MCF-10A

Parental cells

0/3

0/4

—

0/3

0/4

—

IL-6

0/3

0/4

—

0/3

0/4

—

EGF+bFGF

0/3

0/4

—

0/3

0/4

—

TGF-β

0/3

0/4

—

0/3

0/4

—

  1. Abbreviations: bFGF=basic fibroblast growth factor; EGF=epidermal growth factor; IL-6=interleukin-6; TGF-β=transforming growth factor-β.
  2. aThe values denote number of tumours/number of injections.
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