Table 1 Univariate analysis showing the relationship between stage at diagnosis and various factors for patients with CRC
Factor | Overall ( n =868) | Stage A or B ( n =443) | Stage C or D ( n =425) | OR (99% CI) |
|---|---|---|---|---|
Provider delay median (IQR) weeks | 17 (8, 39) | 17 (9, 39) | 17 (8, 39) | 0.99 (0.99, 1.00) |
Age median (IQR) years | 71 (64, 78) | 73 (66, 79) | 70 (62, 76) | 0.98 (0.96, 0.99) |
Gender | ||||
Male | 491 (56.6) | 235 (53.1) | 256 (60.2) | 1.34 (0.94, 1.91) |
Female | 377 (43.4) | 208 (47.0) | 169 (39.8) | 1.00 |
Smoking status | ||||
Non-smoker | 326 (37.6) | 177 (40.0) | 149 (35.1) | 1.00 |
Current smoker | 137 (15.8) | 65 (14.7) | 72 (16.9) | 1.32 (0.78, 2.23) |
Ex-smoker | 191 (22.0) | 99 (22.4) | 92 (21.7) | 1.10 (0.69, 1.77) |
Not known | 214 (24.7) | 102 (23.0) | 112 (26.4) | 1.30 (0.83, 2.05) |
Carstairs quintile | ||||
1 (least deprived) | 207 (24.3) | 98 (22.6) | 109 (26.0) | 1.00 |
2 | 230 (27.0) | 133 (30.7) | 97 (23.1) | 0.66 (0.40, 1.08) |
3 | 206 (24.2) | 100 (23.0) | 106 (25.3) | 0.95 (0.57, 1.58) |
4 | 149 (17.5) | 69 (15.9) | 80 (19.1) | 1.04 (0.60, 1.82) |
5 (most deprived) | 61 (7.2) | 34 (7.8) | 27 (6.4) | 0.71 (0.34, 1.52) |
Charlson index (median (IQR) | 1 (0, 2) | 1 (0, 2) | 1 (0, 2) | 1.14 (1.05, 1.24) |
Place of presentation | ||||
GP surgery | 676 (77.9) | 350 (79.0) | 326 (76.7) | 1.00 |
GP home visit | 111 (12.8) | 59 (13.3) | 52 (12.2) | 0.95 (0.56, 1.61) |
GP out of hours visit | 33 (3.8) | 12 (2.7) | 21 (4.9) | 1.88 (0.72, 4.87) |
Other | 22 (2.5) | 10 (2.3) | 12 (2.8) | 1.29 (0.42, 3.95) |
Not known | 26 (3.0) | 12 (2.7) | 14(3.3) | 1.25 (0.45, 3.52) |
Tumour grade | ||||
I | 42 (4.9) | 36 (8.2) | 6 (1.44) | 1.00 |
II | 550 (64.2) | 293 (66.7) | 257 (61.5) | 5.26 (1.65, 16.74) |
III/IV | 147 (17.2) | 53 (12.1) | 94 (22.5) | 10.6 (3.14, 36.01) |
Ungradeable | 118 (13.8) | 57 (13.0) | 61 (14.6) | 6.42 (1.88, 21.99) |
Type of hospital admission | ||||
Elective admission | 631 (72.7) | 328 (74.0) | 303 (71.3) | 1.00 |
Emergency admission | 237 (27.3) | 115 (26.0) | 122 (28.7) | 1.15 (0.78, 1.70) |
Symptom | ||||
Constipation | 118 (13.6) | 49 (11.1) | 69 (16.2) | 1.56 (0.93, 2.61) |
Rectal bleeding | 252 (29.0) | 140 (31.6) | 112 (26.4) | 0.77 (0.53, 1.14) |
Abdominal pain | 251 (28.9) | 118 (26.6) | 133 (31.3) | 1.25 (0.85, 1.85) |
Anorexia | 34 (3.9) | 12 (2.7) | 22 (5.2) | 1.96 (0.76, 5.03) |
Weight loss | 79 (9.1) | 37 (8.4) | 42 (9.9) | 1.20 (0.65, 2.21) |
Abdominal mass | 49 (5.7) | 29 (6.6) | 20 (4.7) | 0.71 (0.32, 1.52) |
