Table 3 Relationship between patient and tumour factors and symptoms and signs with survival among CRC patients
Factor | Total ( n =958) | Deaths ( n =762) | HR | 99% CI |
|---|---|---|---|---|
Provider delay median (IQR) weeks | 17 (8,39) | 17 (8, 39) | 0.99 | 0.992, 0.999 |
Age median (IQR) years | 71 (64, 78) | 74 (67, 79) | 1.04 | 1.03, 1.05 |
Gender | ||||
Male | 540 (56.4) | 439 (81.3) | 1.18 | 0.98, 1.42 |
Female | 418 (43.6) | 323 (77.3) | 1.00 | |
Smoking status | ||||
Never smoked | 358 (37.4) | 270 (75.4) | 1.00 | |
Current smoker | 149 (15.6) | 117 (78.5) | 1.14 | 0.86, 1.51 |
Ex-smoker | 209 (21.8) | 175 (83.7) | 1.24 | 0.96, 1.59 |
Not known | 242 (25.3) | 200 (82.6) | 1.33 | 1.04, 1.69 |
Carstairs deprivation quintile | ||||
1 (least deprived) | 227 (24.1) | 167 (73.6) | 1.00 | |
2 | 255 (27.0) | 195 (76.5) | 1.05 | 0.80, 1.37 |
3 | 231 (24.5) | 204 (88.3) | 1.43 | 1.09, 1.87 |
4 | 165 (17.5) | 133 (80.6) | 1.32 | 0.97, 1.77 |
5 (most deprived) | 65 (6.9) | 51 (78.5) | 1.17 | 0.77, 1.76 |
Charlson index median (IQR) | 1 (0,2) | 2 (0,2) | 1.16 | 1.12, 1.20 |
Tumour grade | ||||
Grade I | 46 (4.9) | 35 (76.1) | 1.00 | |
Grade II | 571 (60.5) | 434 (76.0) | 1.09 | 0.69, 1.71 |
Grade III/IV | 158 (16.7) | 136 (86.1) | 1.72 | 1.05, 2.80 |
Ungraded | 169 (17.9) | 145 (85.8) | 1.75 | 1.08, 2.85 |
Place of original presentation | ||||
GP surgery | 737 (76.9) | 565 (76.7) | 1.00 | |
GP home visit | 128 (13.4) | 121 (94.5) | 1.86 | 1.43, 2.41 |
GP out of hours visit | 37 (3.9) | 30 (81.1) | 1.12 | 0.69, 1.83 |
Others | 25 (2.6) | 21 (84.0) | 1.39 | 0.78, 2.46 |
Missing | 31 (3.2) | 25 (90.7) | 1.29 | 0.76, 2.18 |
Type of admission | ||||
No emergency admission | 699 (73.0) | 539 (77.1) | 1.00 | |
Emergency admission | 259 (27.0) | 223 (86.1) | 1.47 | 1.19, 1.80 |
Constipation | ||||
Yes | 133 (13.9) | 112 (84.2) | 1.19 | 0.91, 1.55 |
No | 825 (86.1) | 650 (78.8) | 1.00 | |
Rectal bleeding | ||||
Yes | 273 (28.5) | 192 (70.3) | 0.70 | 0.56, 0.87 |
No | 685 (71.5) | 570 (83.2) | 1.00 | |
Abdominal pain | ||||
Yes | 273 (28.5) | 224 (82.1) | 1.14 | 0.93, 1.40 |
No | 685 (71.5) | 538 (78.5) | 1.00 | |
Anorexia | ||||
Yes | 45 (4.7) | 42 (93.3) | 1.88 | 1.25, 2.83 |
No | 913 (95.3) | 720 (78.9) | 1.00 | |
Weight loss | ||||
Yes | 94 (9.8) | 82 (87.2) | 1.33 | 0.98, 1.79 |
No | 864 (90.2) | 680 (78.7) | 1.00 | |
Abdominal mass | ||||
Yes | 57 (6.0) | 48 (84.21) | 1.43 | 0.98, 2.11 |
No | 901 (94.0) | 714 (79.3) | 1.00 | |
