Figure 1

(A ) Observed gemcitabine plasma concentrations ( μ g l⁻¹) vs time (h) after intravenous infusion of 10 mg m⁻² min⁻¹ on day 1. (B) Observed gemcitabine plasma concentrations (μg l⁻¹) vs time (h) after intravenous infusion of 10 mg m⁻² min⁻¹ on day 21.