Figure 1

(a) PTEN positive: using immunoreactive score (IRS) and specimens were defined as positive when score was 7 or greater. (b) PI3K positive: tumours were scored when 50% of the neoplastic cells showed a distinct cytoplasmic staining. (c) p95 expression positive: tumours were scored when ⩽50% cells showed nucleolus and cytoplasmic staining detected with the anti-p95 antibody.