Figure 1
From: Anti-apoptotic role and clinical relevance of neurotrophins in diffuse large B-cell lymphomas
Immunohistochemical staining in DLBCL tumour samples. (A) Examples of NGF, BDNF, TrkA, TrkB, p75NTR stainings are done for a tumour biopsy of GCB and non-GCB DLBCL subtype (× 200) as compared with normal reactive lymph node (RLN). (B) Box-plots analysis showing distribution of total immunostaining scores determined in non-GCB tumour samples (n=22) as compared with GCB (n=29) DLBCL subtype. The horizontal line corresponds to the median value, the box length to the interquartile range. Box whiskers represent the maximum and minimum range excluding any extreme outliers (shown as dots). (C) Enhanced NGF expression is associated with MUM1-positive tumours. Results are expressed as means±s.d. of immunostaining NGF scores. **P<0.01 (Mann–Whitney test). The full colour version of this figure is available at British Journal of Cancer online.
