Table 1 Local hospital (England) and Scottish Health Board guidelines for BRCA testing procedures in patients with ovarian cancer (as of October 2014)

From: UK BRCA mutation testing in patients with ovarian cancer

Centre

BRCA mutation testing process

Cambridge University Hospitals

BRCA testing standard as part of the GTEOC study

The Royal Marsden Hospital

BRCA testing standard as part of the oncogenetic model, began in July 2013

Fully integrated service

University Hospitals Birmingham

BRCA testing of all newly diagnosed high-grade serous ovarian cancer patients began in April 2014

Fully integrated service

The Royal Liverpool University Hospitals

Testing of all high-grade serous ovarian cancer patients at diagnosis

Testing offered to prevalent patients upon entering the clinic

Training/consenting courses available for oncologists

Fully integrated service

Oxford University Hospitals

BRCA testing on request for patients with high-grade serous ovarian cancer

Central Manchester University Hospitals

BRCA testing on request for selected patients

Currently (October 2014) not a fully integrated service but aiming to achieve this status; currently consent can only be obtained through a specialist genetics clinic

Scotland

All ovarian cancer patients are tested for BRCA mutations at diagnosis (funded by the Scottish Health Board)

Consent for BRCA mutation testing is obtained by oncologists

Fully integrated service

  1. Abbreviation: GTEOC, Genetic Testing in Epithelial Ovarian Cancer.