Figure 3
Treatment outcome measures. (A) A box and whisker plot of the volume measured on the first week after treatment (oedema+tumour) of skin cancer; (B) number of animals in each group that presented scab after 6 days of light treatment; (C) illustrative representation to show oedema after 1 day of treatment (left) and scab after 6 days of treatment (right). PDT groups received one scheme illumination 3 h after ALA application (total fluence of 50 J cm−2). fPDT groups received twofold illumination (total fluence of 10 and 40 J cm−2, 3 and 5 h after ALA application, respectively). *P-value<0.05 (Kruskal–Wallis test). The samples were compared in terms of light fractionation effect (PDT/fPDT), iron chelation effect (PDT/DFO+PDT and fPDT/DFO+fPDT) or combination effect (DFO+PDT/DFO+fPDT).
