Table 1 Summary of patients enrolled in the trial and comparison of baseline characteristics between standard care and intervention groups
Variable | Total ( n =131) | Standard care ( n =70) | Intervention ( n =61) | P -value |
|---|---|---|---|---|
Age | ||||
Years (mean±s.d.) | 60.5±10.1 | 60.0±10.9 | 61.1±9.1 | 0.558 |
Sex | ||||
Male | 115 (88) | 59 (84) | 56 (92) | 0.19 |
Female | 16 (12) | 11 (16) | 5 (8) | |
Smoking history | ||||
Non smoker | 26 (20) | 14 (20) | 12 (20) | 0.147 |
Former | 81 (62) | 39 (56) | 42 (69) | |
Current | 24 (18) | 17 (24) | 7 (11) | |
Tumour site | ||||
Oral cavity | 14 (11) | 7 (10) | 7 (11) | 0.885 |
Oropharynx | 101 (77) | 56 (80) | 45 (74) | |
Nasopharynx | 4 (3) | 2 (3) | 2 (3) | |
Hypopharynx | 8 (6) | 3 (4) | 5 (8) | |
Larynx | 2 (1) | 1 (1) | 1 (2) | |
UKP | 1 (1) | 0 (0) | 1 (2) | |
Other | 1 (1) | 1 (1) | 0 (0) | |
T stage | ||||
T0 | 1 (1) | 0 (0) | 1 (2) | 0.111 |
T1 | 8 (6) | 4 (5) | 4 (7) | |
T2 | 44 (34) | 20 (29) | 24 (39) | |
T3 | 37 (28) | 26 (37) | 11 (18) | |
T4 | 41 (31) | 20 (29) | 21 (34) | |
N stage | ||||
N0 | 12 (9) | 7 (10) | 5 (8) | 0.629 |
N1 | 13 (10) | 8 (11) | 5 (8) | |
N2a | 4 (3) | 1 (1) | 3 (5) | |
N2b | 55 (42) | 30 (43) | 25 (41) | |
N2c | 42 (32) | 20 (29) | 22 (36) | |
N3 | 5 (4) | 4 (6) | 1 (2) | |
P16 status | ||||
Positive | 85 (69) | 43 (65) | 42 (72) | 0.385 |
Negative | 39 (31) | 23 (35) | 16 (28) | |
Treatment | ||||
ChemoRT | 123 (94) | 67 (96) | 56 (92) | 0.472 |
Other | 8 (6) | 3 (4) | 5 (8) | |
Chemotherapy | ||||
HD cisplatin | 68 (58) | 36 (56) | 32 (60) | 0.382 |
Weekly cisplatin | 25 (21) | 12 (19) | 13 (25) | |
Cetuximab | 24 (21) | 16 (25) | 8 (15) | |
Weight loss 6 months | ||||
Nil | 51 (39) | 22 (31) | 29 (48) | 0.266 |
<5% | 43 (33) | 27 (39) | 16 (26) | |
5–10% | 22 (17) | 12 (17) | 10 (16) | |
⩾10% | 15 (11) | 9 (13) | 6 (10) | |
Nutritional status | ||||
PGSGA A | 99 (76) | 50 (71) | 49 (80) | 0.237 |
PGSGA B | 32 (24) | 20 (29) | 12 (20) | |
PGSGA C | 0 (0) | 0 (0) | 0 (0) | |
Diet | ||||
Full | 87 (66) | 47 (67) | 40 (66) | 0.579 |
Soft | 35 (27) | 20 (29) | 15 (25) | |
Minced | 8 (6) | 3 (4) | 5 (8) | |
Puree | 1 (1) | 0 (0) | 1 (1) | |
Anthropometry | ||||
Weight (kg) | 82.6±18.7 | 79.7±18.7 | 85.8±18.4 | 0.063 |
Fat-free mass (kg) | 59.2±10.4 | 57.6±10.5 | 60.9±10.1 | 0.073 |
BMI (kg m−2) | 27.2±5.5 | 26.4±5.7 | 28.1±5.2 | 0.078 |
Nutrition risk | ||||
PGSGA score (median, range) | 6 (1–21) | 6 (1–21) | 5 (1–20) | 0.052 |
