Table 2 Summary of unadjusted and adjusted linear regression analysis for the effect of the early nutrition intervention on nutrition outcomes in patients with head and neck cancer

From: Randomised controlled trial of early prophylactic feeding vs standard care in patients with head and neck cancer

 

Comparison of outcomes between groups

Summary of regression analysis for the effect of early nutrition intervention on outcomes (ref: standard care)

 

Standard care

Intervention

Unadjusted

Adjusted for baseline differences

Adjusted in full multivariable model

Outcome variable

Mean±s.d.

β

P -value

β

P -value

β

s.e.

95% CI

P -value

Weight (% change)

−10.9±6.6

−10.8±5.6

0.1

0.93

1.01

0.326

0.48

0.98

−1.46

2.43

0.624

Fat-free mass (% change)

−4.2±4.9

−6.3±5.4

−2.06

0.036*

−1.51

0.104

−1.22

0.92

−3.03

0.6

0.187

Fat mass (% change)

−28.5±16.7

−22.7±15.2

5.85

0.056

NA

NA

1.72

2.64

−3.52

6.96

0.515

PGSGA risk score (change)

3.2±6.0

3.7±5.3

0.45

0.665

−0.52

0.534

−0.28

0.86

−1.98

1.42

0.743

SGA nutritional status (% decline)

31%

26%

OR 0.79

0.551

NA

NA

OR 0.78

1.55

0.33

1.83

0.569

  1. Abbreviations: PGSGA=Patient-Generated Subjective Global Assessment; SGA=Subjective Global Assessment. *P<0.05.