Table 1 Univariable and multivariable cox regression analysis of OS by baseline characteristics in all patients

From: Long-term results and recurrence patterns from SCALOP: a phase II randomised trial of gemcitabine- or capecitabine-based chemoradiation for locally advanced pancreatic cancer

 

OS (months) a

Univariable

Multivariable

 

n

Median

95% CIs

HR

95% CIs

P

HR

95% CIs

P

Age

         

 <65

52

11.7

9.8–14.6

1.00

  

1.00

  

 ⩾65

42

14.1

11.1–17.6

0.77

0.50–1.19

0.237

0.54

0.33–0.88

0.013

Sex

         

 Male

51

13.9

11.3–16.5

1.00

  

1.00

  

 Female

43

11.9

9.3–14.1

1.01

0.65–1.56

0.964

1.12

0.69–1.80

0.654

WHO performance status

         

 0

45

16.5

12.7–21.5

1.00

  

1.00

  

 1–2

49

11.1

8.1–12.7

2.05

1.32–3.17

0.001

2.09

1.24–3.52

0.006

CA19.9

         

 <613

54

16.5

13.9–19.7

1.00

  

1.00

  

 ⩾613

40

9.7

7.6–10.7

3.38

2.11–5.43

<0.001

4.11

2.38–7.12

<0.001

Global heath statusb

   

0.97

0.89–1.06

0.549

0.95

0.85–1.06

0.395

Longest diameterc

   

1.12

0.97–1.29

0.131

1.28

1.08–1.51

0.005

  1. aFrom registration into SCALOP trial prior to induction CT.
  2. bHRs were calculated for every 10-point difference in scores.
  3. cHRs calculated for every 1 cm increase.
Back to article page