Figure 7
From: New insights into the vitamin D requirements during pregnancy
Weighted Co-expression Network Analysis (WGCNA) was carried out on 5839 differentially expressed probes identified by SigGenes. 14 co-expression modules were identified and, correlated to various clinical traits. Gene network, represented by different colored coded co-expression modules (y axis) and their association with various clinical traits (x axis). The intensity of the colors indicates the strength of the relationships, as indicated by the scale to the right. The range of the scale (+1 to −1) indicates either positive (+1) or negative (−1) correlation with a specific clinical trait. Top number in each box corresponds to the Pearson’s correlation coefficient between a module and a specific trait, while the lower number represents its P-value. Traits: ppbmi=pre-pregnancy BMI; gestdays=gestational age; basev=vitamin D levels in first trimester; latev=vitamin D levels in third trimester; mother.race=maternal race (White/African-American); Child.gender+infant gender (boy/girl). Pearson’s correlation (P<0.05). Reproduced with permission from Al-Garawi et al.128
