Figure 1 | Cell Death & Disease

Figure 1

From: Activation of mTOR coincides with autophagy during ligation-induced atrophy in the rat submandibular gland

Figure 1

Gland weights (a) and Alcian Blue/PAS staining (b–h) of submandibular glands with increasing periods of ligation. (Panel a) Mean weight±S.D. of glands after 0, 1, 3, 5, 7, 9 and 14 days of ligation. n=3 for all time points. (Panel b) Control: unoperated submandibular gland showing the typical appearance of acini (purple) and ductal (pink) cells. (Panel c) In 1-day ligated: large numbers of inflammatory cells invaded the stroma and interstitial spaces (arrows). (Panels d and e) In 3–5-day ligated: considerable reduction of secretory proteins was seen. (Panel f) In 7-day ligated: little staining of secretory protein was apparent. (Panel g) In 9-day ligated: luminal dilation of ducts (arrow) shows some blue staining. (Panel h) In 14-day ligated: sub-population of acinar cells (arrow head) along the periphery of the gland continues to show the presence of secretory protein

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