Table 1 Identification of ductal cell-specific genes that are highly expressed in unoperated control glands, but then subsequently downregulated in the 2-week ligated (atrophic) glands (n=3 for both groups)

From: Activation of mTOR coincides with autophagy during ligation-induced atrophy in the rat submandibular gland

Accession no.

Ductal gene description

Functional category

Fold change

BI279260

EST: Highly similar to glandular kallikrein 10 precursor

Kallikrein-like serine proteases

333↓

NM_012593.1

Kallikrein 7, renal/pancreas/salivary (Klk7)

Serine protease family

256↓

BI279353

EST: (clone RSKG50) kallikrein mRNA, 3 end kallikrein 3

Serine protease family

110↓

NM_012677

Tonin (Ton) (alias Klk2)

Kallikrein subfamily

100↓

M11566

Submaxillary gland S3 kallikrein mRNA (Klks3)

Serine protease family

97↓

NM_012842

Epidermal growth factor (Egf)

Growth Factor

83↓

AI169562

EST: (clone K-32) kallikrein mRNA, 3 end (RGD:735228)

Serine protease family

75↓