Figure 5 | Cell Death & Disease

Figure 5

From: BRCC2 inhibits breast cancer cell growth and metastasis in vitro and in vivo via downregulating AKT pathway

Figure 5

BRCC2 inhibited tumorigenesis and metastasis in vivo. (a) Growth curves of mammary tumors after the injection of BRCC2-overexpressing MDA-MB-231 and control cells into SCID mice. The error bars represent the means±S.D. (n=6). (b) Growth curves of mammary tumors after the injection of BRCC2-silenced T47D and control cells into SCID mice. The error bars represent the means±S.D. (n=6). (c) Representative tumors are presented from the experiments that were outlined in a and b. (d) Representative lungs that were harvested from the mice that had been injected in the lateral tail veins. (e) Representative hematoxylin and eosin staining of lung sections (magnification, × 40). The right panel is the high magnification (magnification, × 100) image for the picture that is marked in the box. Each group consisted of ten mice

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