Figure 6
Analysis of cell death in PRSS1 transgenic mice pancreatic tissue sections. (a) Representative images of immunohistochemical analysis of pancreatic tissue sections isolated from animals from each transgenic strain and matched wild-type (WT) control, as indicated, using antibodies specific for cleaved caspase-3. Original magnification × 200. (b) Quantification of immunohistochemical detection of cleaved caspase-3. (c) Representative images of TUNEL analysis of pancreatic tissue sections isolated from animals from each transgenic strain and matched WT control, as indicated. Insets represent magnified areas of the photomicrographs showing punctuate TUNEL-positive staining characteristic of an apoptotic cell (original magnification × 200). (d) Quantification of TUNEL assay data
