Figure 7
From: Non-apoptotic functions of caspase-7 during osteogenesis
Activation of caspase-3 (c–f), distribution of apoptotic cells (g–j), and expression of osteocalcin (k–n) in Casp7−/− (a, c, d, g, h, k, l) versus wild-type mice (b, e, f, i, j, m, n) at ED15.5, and spatial correlation of caspase-3 (o) and caspase-7 (p) in wild-type mice at P0. Morphology of mandible visualised by haematoxylin-eosin staining in Casp7−/− (a) and wild-type mice (b). White arrows point to the positive cells (brown), yellow arrows point to cells with activation of caspase-3 and caspase-7, red arrows point to cells where solely caspase-7 is activated; C3 (caspase-3), C7 (caspase-7), man (mandibular bone), mec (Meckel's cartilage), OS (osteocalcin). Scale bar=100 μm
