Figure 1 | Cell Death & Disease

Figure 1

From: An unexpected role for caspase-2 in neuroblastoma

Figure 1

Caspase-2 deficiency delays the onset of MYCN-mediated neuroblastoma. (a) Comparison of Kaplan–Meier survival curves of TH-MYCN mice (Sv129J mouse background, n=30) and TH-MYCN mice (C57Bl6/Sv129J mixed background; n=31). P-value determined by log-rank (Mantel cox) test. (b) Survival curves of TH-MYCN/Casp2+/+, TH-MYCN/Casp2+/− and TH-MYCN/Casp2−/− mice (C57BL6/Sv129J mixed littermates). P-value for TH-MYCN/Casp2+/+ compared with TH-MYCN/Casp2−/− mice was determined by log-rank test, with P<0.05 being significant

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