Figure 5 | Cell Death & Disease

Figure 5

From: An unexpected role for caspase-2 in neuroblastoma

Figure 5

Ras signaling in TH-MYCN/Casp2−/− neuroblastoma. Western blots showing expression levels of MYCN and Ras pathway components; Ras, Erk1/2, phospho-Erk1/2, Akt, phospho-Akt in (a) abdominal and (b) thoracic tumors from TH-MYCN/Casp2+/+ and TH-MYCN/Casp2−/− mice. Caspase-2 deficiency was validated by western blotting with anti-Caspase-2 antibody. Samples were run on three separate blots, with β-actin shown as a loading control

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