Figure 1

Expression of CTGF and VEGF in normal and osteoarthritis (OA) patients. (a) Synovial fluid was obtained from normal or OA patients and conditioned medium (CM) from normal or OA synovial fibroblasts, CTGF and VEGF expression examined by ELISA. (b) Correlation between CTGF and VEGF expression in synovial fluid of OA patients. (c and d) Normal and OA synovial fluid or normal and OA synovial fibroblast CM were applied to EPCs for 24 h, capillary-like structure formation and migration in EPCs examined by tube formation and Transwell assay. Results are expressed as the mean±S.E.M. *P<0.05 compared with normal patients