Table 1 Association between Gal-3 expression and clinical-pathological features in a cohort of NTs

From: Galectin-3 is a marker of favorable prognosis and a biologically relevant molecule in neuroblastic tumors

 

Total

Gal-3-positive

  

n

%

P

Age (months)

    

 <15

39

6

15.4

0.25

 ⩾15

89

23

25.8

 

 Total

128

   

Sex

    

 Female

68

17

25.0

0.53

 Male

60

12

20.0

 

 Total

128

   

Primary site

    

 Adrenal

58

10

17.2

0.21

 Nonadrenal

70

19

27.1

 

 Total

128

   

a Stage

    

 1-2-4s

47

10

21.3

0.81

 3-4

76

14

18.4

 

 Total

123

   

(INPC) Shimada

    

 Favorable

76

25

32.9

0.001

 Unfavorable

52

4

7.7

 

 Total

128

   

a MYCN

    

 Nonamplified

89

21

23.6

0.12

 Amplified

31

3

9.7

 

 Total

120

   

(INPC) Tumor histology

    

 NB

104

12

11.5

<0.001

 GNB

19

12

63.2

 

 GN

5

5

100.0

 

 Total

128

   

 dNB

25

8

32.0

0.001

 pdNB

61

3

4.9

 

 udNB

18

1

5.6

 

 Total

104

   
  1. Abbreviations: dNB, differentiating NB; pdNB, poorly differentiated NB; udNB, undifferentiated NB
  2. P=Two-tailed Fisher's exact test except for INPC and NB differentiated where Pearson’s χ2-test was used. Statistically significant values are in bold
  3. aGN is not included in this category
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