Figure 1 | Cell Death & Disease

Figure 1

From: Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cells

Figure 1

Overview of the GLI-binding sites and their position in the human survivin promoter. Numbering is from initiating ATG (+1). Full consensus sites and the sequence used for introduced mutations is also given. Black letters are consensus nucleotides, light letters are non-consensus nucleotides. Survivin-containing GLI sites are degenerated in 1–3 nucleotides. GLI site positions are shown in Figure 2

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