Table 1 The summary of the receptor/ligand pairs required for pDTP toxicity in different cell lines (↑ indicates increasing the cytotoxicity;↓indicates decreasing the cytotoxicity; − indicates little effect)
From: In situ generated D‐peptidic nanofibrils as multifaceted apoptotic inducers to target cancer cells
Cells | HeLa | MES-SA/Dx5 | T98G | A2780-cis |
|---|---|---|---|---|
mAbs | ||||
Anti-TNFR1 | ↑ | ↓ | − | − |
Anti-TNFR2 | ↑ | ↓ | ↓ | ↓ |
Anti-TNF-α | ↓ | ↓ | ↓ | − |
TNF-α | ↑ | − | ↑ | − |
Anti-DR3 | ↑ | − | − | − |
Anti-DR4 | ↑ | ↑ | ↑ | − |
Anti-DR5 | − | ↓ | − | − |
Anti-TRAIL | ↓ | − | − | ↑ |
TRAIL | ↑ | − | ↑ | − |
Anti-CD95 | ↓ | − | − | − |
Anti-CD95L | ↑ | − | ↑ | − |
CD95L | ↓ | ↓ | ↑ | ↓ |
