Table 2 Univariate and multivariate analysis of TTR in different Cezanne expressions of HCC patients
From: Cezanne predicts progression and adjuvant TACE response in hepatocellular carcinoma
Variables | Low Cezanne expression | High Cezanne expression | ||||||
|---|---|---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | |||||
P -value | P -value | HR | 95% CI | P -value | P -value | HR | 95% CI | |
Gender (female versus male) | NS | NS | NS | NS | ||||
Age, years (⩽50 versus >50) | NS | NS | NS | NS | ||||
AFP (ng/ml) (⩽400 versus >400) | NS | NS | 0.050 | NS | ||||
HBsAg (negative versus positive) | 0.018 | NS | 0.007 | 0.019 | 0.445 | 0.226–0.874 | ||
GGT (U/l) (⩽50 versus >50) | NS | NS | <0.001 | NS | ||||
Liver cirrhosis (no versus yes) | 0.001 | 0.018 | 1.767 | 1.104–2.828 | NS | NS | ||
Tumor size (cm) (⩽5 versus >5) | 0.023 | 0.001 | 1.843 | 1.298–2.617 | <0.001 | 0.005 | 2.218 | 1.265–3.899 |
Tumor number (single versus multiple) | NS | NS | <0.001 | 0.023 | 2.025 | 1.103–3.718 | ||
Satellite nodule (no versus yes) | NS | NS | 0.003 | NS | ||||
Tumor capsule (no/ incomplete versus complete) | NS | NS | NS | NS | ||||
Tumor differentiation (I–II versus III–IV) | NS | NS | NS | NS | ||||
Vascular invasion (no versus yes) | NS | NS | 0.002 | NS | ||||
Adjuvant TACE (no versus yes) | 0.002 | 0.002 | 0.568 | 0.397–0.812 | <0.001 | NS | ||
