Figure 1 | Cell Death & Disease

Figure 1

From: DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway

Figure 1

DCZ3301 inhibits the proliferation of the DLBCL cell lines. (a) The chemical structure of DCZ3301. (b) DLBCL cell lines (OCI-LY8, NU-DUL-1 SUDHL-4, DB and TMD8) were treated with DCZ3301 (1, 2, 4, 8, 16 and 32 μM) in 96-well plates for 48 h. (c) OCI-LY8 and (d) NU-DUL-1 cell lines were treated with DCZ3301 (1, 2, 4, 8, 16 and 32 μM) in 96-well plates for 24, 48 and 72 h. (e) OCI-LY8 and (f) NU-DUL-1 cells were treated with the indicated concentrations of DCZ3301 for 48 h in the presence or absence of either 50 nM IL-6 or 25 nM IGF-1 for 24, 48 and 72 h. The processed cells were followed by assessment for cell proliferation using CCK-8

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