Figure 1

Rapamycin protects mice kidney against AKI in vivo. (a) The level of serum creatinine (μmol/l) and blood urea nitrogen (mmol/l) on POD 1 and POD 2. (b)The histological image of H&E-stained kidney tissue (× 200). Semi-quantitative analysis was performed following histological scoring system. (c) Immunohistochemical staining of CD4 and CD8 in kidney tissue (× 200). The black arrow pointed to the positive cells. The average number of positive cells per field was analyzed. (data were shown as mean±S.D.; n=5 mice per group per time point; POD, postoperative day)