Figure 5 | Cell Death & Disease

Figure 5

From: The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury

Figure 5The alternative text for this image may have been generated using AI.

mTOR signal regulates the induction of MDSCs from bone marrow cells. (a) CD11b+ cells were gated first, and Ly-6G+Ly-6Clow and Ly-6G−Ly-6Chigh cell populations were detected within CD11b+ cells. In comparison with control, rapamycin treatment directed MDSC induction towards Ly-6G+Ly-6Clow G-MDSC subtype. (b) After 100 nM rapamycin or equal volume of DMSO treatment for 4 h, the frequencies of CD4+IFN-γ+ Th1 cells, CD4+IL-17a+ Th17 cells and CD8+IFN-γ+ T cells were examined by using flow cytometry, respectively. (data were shown as mean±S.D.; n=5 duplicate tests)

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