Figure 2 | Cancer Gene Therapy

Figure 2

From: RETRACTED ARTICLE: VP2 capsid domain of the H-1 parvovirus determines susceptibility of human cancer cells to H-1 viral infection

Figure 2

H-1-specific tropism is also reproduced in human A549 and Panc-1 cancer cells. (a and b) A549 lung and Panc-1 human cancer cells were infected with chimeric viruses (CH1–5), and the parental KRV and H-1 parvoviruses (multiplicity of infection (MOI)=1). The cell viability was observed by light microscopy 72 h after infection. The viable cells were counted with trypan blue exclusion 72 h after infection. Average of results from triplicate wells were obtained and the error bars indicates s.e.m. (*P<0.01; H-1, CH4 or CH5 vs KRV). (c) The cell lysates were prepared 72 h after infection and the VP2 capsid proteins of KRV and H-1 virus, and PARP were detected using the corresponding antibodies.

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