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Constrained human genes under scrutiny

A higher number of damaging variations in certain genes is associated with an increased likelihood that a man will be childless. A geneticist and an anthropologist discuss what can — and can’t — be learnt from this finding.
By
  1. Loic Yengo

    1. Loic Yengo is at the Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia.

  2. Heidi Colleran

    1. Heidi Colleran is in the BirthRites Independent Max Planck Research Group and the Department of Human Behavior, Ecology and Culture, Max Planck Institute for Evolutionary Anthropology, 04103 Leipzig, Germany.

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Nature 603, 799-801 (2022)

doi: https://doi.org/10.1038/d41586-022-00693-4

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Competing Interests

The authors declare no competing interests.

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