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Neanderthals might have lived in small groups, with females regularly arriving and leaving.Credit: S. Plailly/E. Daynes/SPL
A Neanderthal nuclear family
For the first time, researchers have identified a set of closely related Neanderthals: a father, his teenage daughter and two other more distant relatives. The discovery of the family and seven more individuals in Chagyrskaya Cave in southern Siberia, along with two more from a nearby site, nearly doubles the number of known Neanderthal genomes. Genetic clues found in the individuals’ DNA hint that the population of breeding adults was low, and that there was more diversity in maternally inherited mitochondrial genomes — suggesting that mothers left their communities to build new families.
Reference: Nature paper
Orangutan genome mix-up
A landmark genetic study of orangutans mistakenly muddled which sequences belonged to which species, with knock-on effects on hundreds of subsequent manuscripts. The slip-up might have implications for captive breeding programmes, which try to avoid hybridizing orangutan species. It also highlights how easy it can be for mistakes to enter the scientific record. “In some ways, we’re lucky that this was just orangutans,” says Graham Banes, who led a reanalysis of the flawed paper. “What if this was a biomedical paper and people were developing therapies based on published data?”
References: Original Nature paper (now corrected) & Scientific Data paper that reveals the mistake
The lasting legacy of bubonic plague
The bubonic plague, which was caused by the bacterium Yersinia pestis, might have left its mark on the genes involved in the modern human immune system. Four DNA variants, in particular, seem to have become more common after the Black Death, and might have contributed to survival. The protection afforded by those variants could have come at a cost: today, two of them are associated with an increased risk of autoimmune disorders, such as Crohn’s disease and rheumatoid arthritis.
Read more: evolutionary biologist David Enard analyses the research in the Nature News & Views article (5 min read, Nature paywall)
Where I work

Damian Cohall is a senior lecturer and head of preclinical and health sciences at the University of the West Indies, Cave Hill, in Barbados.Credit: Micah B. Rubin for Nature
“Across the Caribbean, medicinal plants grow everywhere,” says pharmacologist Damian Cohall, shown here with a West Indian bay tree (Pimenta racemosa) and wearing a dashiki gifted to him on a visit to Ghana. “When I started studying plants and their historical uses, I realized there was a greater mission — to understand the culture of our ancestors,” he says. “I’m using ethnopharmacology to try to change the narrative on what traditional medicine is: to show that it is indeed scientific, and always has been.”
(Nature | 3 min read) (Micah B. Rubin for Nature)
