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  • NEWS FEATURE

Dozens of new obesity drugs are coming: these are the ones to watch

Next-generation obesity drugs will work differently from Ozempic and Wegovy — aiming to deliver greater weight loss with fewer side effects.
By
  1. Elie Dolgin

    1. Elie Dolgin is a science journalist in Somerville, Massachusetts.

Conceptual illustration showing a group of people with a broad range of drugs to choose from.

Illustration: Zofia Chamienia

For Kristian Cook, every pizza box he opened was another door closed on the path to overcoming obesity. “I had massive cravings for pizza,” he says. “That was my biggest downfall.”

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Nature 638, 308-310 (2025)

doi: https://doi.org/10.1038/d41586-025-00404-9

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