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Will mpox go global again? Research shows it’s evolving in curious ways

Analyses of monkeypox virus clades currently in circulation provide clues to how the virus managed to spread worldwide in 2022 — and how it might go global again.
By
  1. Max Kozlov

As mpox continues to spark localized outbreaks in Africa and, on occasion, in other parts of the world, researchers are racing to understand how the virus managed to spread globally in 2022 — and how it might do so again.

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Nature 649, 533-534 (2026)

doi: https://doi.org/10.1038/d41586-025-04154-6

References

  1. Swan, C. L. et al. Preprint at bioRxiv https://doi.org/10.64898/2025.12.16.694558 (2025).

  2. Kaiser, F. K. et al. Preprint at bioRxiv https://doi.org/10.64898/2025.12.09.693236 (2025).

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