Figure 1

Volcano plots for proportion of total energy intake derived from fat (a) and (MUFA+PUFA)/SFA (b). The regression coefficient refers to the coefficient of the linear model and each point represents a CpG site or a CpG island. The red horizontal line is the significance threshold (P-value=0.05) and all points above this line are significant. (a) proportion of total energy intake derived from fat (positive coefficients refer to an increased methylation in children for whom fat represents a higher proportion of total energy intake). (b) (MUFA+PUFA)/SFA (positive coefficients refer to an increased methylation in children having a higher (MUFA+PUFA)/SFA).