Table 3 Age-stratified (>60 and ≤60) associations between APOE and cognitive ability adjusted for age and sex
Logical memory | Verbal fluency test | Digit symbol test | Mill Hill vocabulary scale | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta | SE | P | Beta | SE | P | Beta | SE | P | Beta | SE | P | |
Age >60 years | ||||||||||||
e4 (additive) | −0.095 | 0.033 | 0.003 | 0.075 | 0.033 | 0.023 | −0.087 | 0.030 | 0.004 | −0.026 | 0.033 | 0.423 |
e4 (yes vs no) | −0.090 | 0.037 | 0.016 | 0.070 | 0.038 | 0.064 | −0.082 | 0.034 | 0.017 | −0.025 | 0.038 | 0.504 |
e2e2 | 0.075 | 0.225 | 0.614 | −0.219 | 0.227 | 0.317 | −0.205 | 0.206 | 0.352 | 0.020 | 0.224 | 0.928 |
e2e3 | −0.079 | 0.051 | 0.326 | −0.049 | 0.051 | 0.181 | 0.032 | 0.047 | 0.220 | 0.026 | 0.051 | 0.515 |
e2e4 | −0.087 | 0.112 | 0.606 | 0.055 | 0.113 | 0.738 | −0.079 | 0.103 | 0.583 | −0.016 | 0.113 | 0.930 |
e3e4 | −0.080 | 0.041 | 0.096 | 0.042 | 0.041 | 0.425 | −0.057 | 0.038 | 0.219 | −0.015 | 0.041 | 0.770 |
e3e3 | — | — | — | — | — | — | — | — | — | — | — | — |
e4e4 | −0.321 | 0.108 | 0.003 | 0.232 | 0.110 | 0.034 | −0.272 | 0.100 | 0.006 | −0.076 | 0.109 | 0.484 |
Age ≤60 years | ||||||||||||
e4 (additive) | −0.013 | 0.016 | 0.425 | 0.044 | 0.016 | 0.008 | −0.007 | 0.015 | 0.638 | 0.042 | 0.015 | 0.007 |
e4 (yes vs no) | −0.006 | 0.019 | 0.748 | 0.054 | 0.019 | 0.004 | −0.004 | 0.017 | 0.806 | 0.050 | 0.018 | 0.004 |
e2e2 | −0.031 | 0.104 | 0.830 | −0.020 | 0.104 | 0.769 | −0.046 | 0.098 | 0.560 | −0.048 | 0.097 | 0.534 |
e2e3 | −0.023 | 0.026 | 0.443 | −0.003 | 0.027 | 0.477 | 0.045 | 0.025 | 0.066 | −0.006 | 0.025 | 0.350 |
e2e4 | −0.033 | 0.055 | 0.597 | −0.031 | 0.055 | 0.316 | −0.031 | 0.051 | 0.527 | 0.070 | 0.051 | 0.305 |
e3e4 | −0.0005 | 0.020 | 0.816 | 0.063 | 0.020 | 0.002 | 0.009 | 0.019 | 0.551 | 0.047 | 0.019 | 0.021 |
e3e3 | — | — | — | — | — | — | — | — | — | — | — | — |
e4e4 | −0.085 | 0.051 | 0.098 | 0.039 | 0.051 | 0.443 | −0.031 | 0.048 | 0.522 | 0.050 | 0.048 | 0.296 |
