Table 1 Cell viability of Fe65 WW domain mutant, Nedd4-2 AL mutant, or its wild type. _{EGFP Nedd4-2 (wt) or its EGFP Nedd4-2 AL mutant or EGFP vector were transfected HEK 293 cells and the rate of apoptosis measured by FACS. EGFP Nedd4-2 mutant (not merged with Fe65) or EGFP Fe65 WW domain mutant significantly promoted cell survival, compared to Nedd4-2 (wt) or Fe65 (wt) constructs. For details, see Methods. Mean value of 5 repeats}

From: Ubiquitylation of Fe65 adaptor protein by neuronal precursor cell expressed developmentally down regulated 4-2 (Nedd4-2) via the WW domain interaction with Fe65