Figure 7

Effects of baicalein on ER stress-induced reduction of MMP in HT22 neuronal cells. HT22 cells were pretreated with 50 µM baicalein or 5 mM NAC, and treated with 5 µM TG, 10 µM BFA, or 10 µM rotenone for 6 h (A, B). The cells were then stained with DiOC6 and the fluorescence was detected by flow cytometry as described in the Materials and Methods section (A). Percent MMP was calculated and plotted in the graph (B). *P < 0.01 when compared with untreated control cells. #P < 0.01 when compared with TG-, BFA-, or rotenone-treated cells without baicalein or NAC.