Figure 2 | Experimental & Molecular Medicine

Figure 2

From: Nanocurcumin–pyrroloquinoline formulation prevents hypertrophy–induced pathological damage by relieving mitochondrial stress in cardiomyocytes under hypoxic conditions

Figure 2

The effect of nanocurcumin formulation (NCF) on hypoxia-induced hypertrophy in human ventricular cardiomyocytes (HVCM) cells. Increments in cell size (× 40) (a, b) along with atrial natriuretic factor (ANF) and brain natriuretic peptide (BNP) levels (c) depicted hypertrophic growth. Increments in FITC-leucine and FITC-phenylalanine uptake further confirmed hypoxia-induced hypertrophy (d). NCF supplementation effectively modulated hypoxia-induced hypertrophy in vitro. Data are expressed as the means±s.d. Values were considered to be statistically significant at *P⩽0.05 vs NVC, **P⩽0.01 vs NVC, #P⩽0.05 vs HVC and ##P⩽0.01 vs HVC. Non-significant changes are depicted as NS. Scale bar, 20 μm.

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