Abstract
Purpose
To assess the relationship between age and the incidence and severity (determined by a grading system) of pinguecula in contact lens (CL) wearers, and to compare the grade of pinguecula between CL wearers and non-wearers.
Methods
A total of 600 CL wearers (94 wore hard CLs (HCLs) and 506 wore soft CLs (SCLs)) aged 11–60 years and 579 non-wearers aged 10–60 years were enrolled. The age, gender, medical history, ocular history, and grade of pinguecula at two locations (nasal and temporal) were determined in all subjects.
Results
There was an age-related increase in the grade of pinguecula among both CL wearers and non-wearers. The grade of pinguecula at the temporal conjunctiva was higher in CL wearers than in non-wearers (P=0.01907), whereas it was higher in HCL wearers than SCL wearers at both the nasal and temporal conjunctiva (P<0.00001 and P<0.00001).
Conclusions
This was the first assessment of the severity of pinguecula in a large consecutive series of CL wearers. Our results suggest that the use of CLs is an important risk factor for pinguecula.
Similar content being viewed by others
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Archila EA, Arenas MC . Etiopathology of pinguecula and pterigium. Cornea 1995; 14: 543–544.
Panchapakesan J, Hourihan F, Mitchell P . Prevalence of pterygium and pinguecula: the Blue Mountains Eye Study. Aust N Z J Ophthalmol 1998; 26 (Suppl 1): S2–S5.
Lim R, Mitchell P, Cumming RG . Cataract associations with pinguecula and pterygium: the Blue Mountains Eye Study. Am J Ophthalmol 1998; 126: 717–719.
Pham TQ, Wang JJ, Rochtchina E, Mitchell P . Pterygium/pinguecula and the five-year incidence of age-related maculopathy. Am J Ophthalmol 2005; 139: 536–537.
Pham TQ, Wang JJ, Rochtchina E, Mitchell P . Pterygium, pinguecula, and 5-year incidence of cataract. Am J Ophthalmol 2005; 139: 1126–1128.
Fotouhi A, Hashemi H, Khabazkhoob M, Mohammad K . Prevalence and risk factors of pterygium and pinguecula: the Tehran Eye Study. Eye 2009; 23: 1125–1129.
Mimura T, Yamagami S, Usui T, Funatsu H, Mimura Y, Noma H et al. Changes of conjunctivochalasis with age in a hospital-based study. Am J Ophthalmol 2009; 147: 171–177.
Mimura T, Usui T, Yamamoto H, Yamagami S, Funatsu H, Noma H et al. Conjunctivochalasis and Contact Lenses. Am J Ophthalmol 2009; 148: 20–25.
Holden BA . The Glenn A. Fry Award lecture 1988: the ocular response to contact lens wear. Optom Vis Sci 1989; 66: 717–733.
Holden BA, Sweeney DF, Seger RG . Epithelial erosions caused by thin high water content lenses. Clin Exp Optom 1986; 69: 103–107.
Guillon JP . Tear film structure on contact lenses. In: Holly FJ (ed). The Preocular Tear Film in Health, Disease, and Contact Lens Wear. Dry Eye Institute: Lubbock (TX), 1986, pp 914–919.
Bergmanson JP, Sheldon TM . Ultraviolet radiation revisited. CLAO J 1997; 23: 196–204.
Harris MG, Haririfar M, Hirano KY . Transmittance of tinted and UV-blocking disposable contact lenses. Optom Vis Sci 1999; 76: 177–180.
Court JL, Redman RP, Wang JH, Leppard SW, Obyrne VJ, Small SA et al. A novel phosphorylcholine-coated contact lens for extended wear use. Biomaterials 2001; 22: 3261–3272.
Acknowledgements
We thank Dr Norihiko Yokoi of the Kyoto Prefectural University of Medicine, for helpful discussions and suggestions.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no conflict of interest.
Rights and permissions
About this article
Cite this article
Mimura, T., Usui, T., Mori, M. et al. Pinguecula and contact lenses. Eye 24, 1685–1691 (2010). https://doi.org/10.1038/eye.2010.120
Received:
Revised:
Accepted:
Published:
Issue date:
DOI: https://doi.org/10.1038/eye.2010.120


