Fig. 1

Left panel: partial genomic DNA sequence of exon 8 of the ATP7B gene shows a homozygosity of Arg778Leu (R778L) mutation. Right panel: PCR—restriction fragment length polymorphism analysis using Msp I for screening of the mutation (R778L) in exon 8 of the ATP7B gene (lane 1: normal; lane 2: homozygote).